Idax proteín
PubMed
2013 May 2;497(7447):122-6. doi: CXXC Finger Protein 4; IDAX; Dvl-Binding Protein IDAX (Inhibition Of The Dvl And Axin Complex); Inhibition Of The Dvl And Axin Complex Protein; CXXC-Type Since this Dvl-interacting protein is a novel protein, we designated it Idax (for inhibition of the Dvl and Axin complex). The mRNA of Idaxwas highly expressed in CXXC-type zinc finger protein 4. Gene -Experimental evidence at protein leveli. This indicates the type of evidence that Synonyms:IDAX.
This subsection 7 Apr 2013 Unexpectedly, IDAX expression results in caspase activation and TET2 protein downregulation, in a manner that depends on DNA binding Synonyms: 9330210J02Rik, C030003J12Rik, CXXC-type zinc finger protein 4, Idax, Inhibition of the Dvl and axin complex protein.
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Source : HEK 293 cells: Species : Human: Components : This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl … 03/08/2019 brain development as loss of Idax by morpholinos in Xenopus tadpoles result in severe forebrain defects (13). In a systematic attempt to increase the understanding of the mechanisms underlying cell context-specific responses of telencephalic neural stem cells (NSCs) to BMP4 signaling dur-ing forebrain development, we have pursued gene expression The cysteine-rich protein Idax acts as a negative regulator of Wnt signaling in mammals by interaction with Dvl in the region of the PDZ domain. In an effort to clarify the st … Dishevelled (Dvl) is the essential signal transduction component of both canonical and non-canonical Wnt signaling pathways. Anti-Idax antibodies can be readily obtained from commercial sources. The Idax protein is a reported synonym for the human gene CXXC4, encoding CXXC finger protein 4. The full-length protein is 198 amino acids in length and 20978 daltons in mass.
Synonyms: 9330210J02Rik, C030003J12Rik, CXXC-type zinc finger protein 4, Idax, Inhibition of the Dvl and axin complex protein. London, T.B. et al., Hino, S. et
The mRNA of Idaxwas highly expressed in CXXC-type zinc finger protein 4. Gene -Experimental evidence at protein leveli.
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27] K04507 CACYBP, SIP; calcyclin binding protein K04508 TBL1; transducin (beta)-like 1 K04510 VANGL; vang-like K04511 PRICKLE; prickle K04512 DAAM; dishevelled associated activator of morphogenesis K04513 RHOA; Ras homolog gene family, member A K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II …
2013 May 2;497(7447):122-6. doi: CXXC Finger Protein 4; IDAX; Dvl-Binding Protein IDAX (Inhibition Of The Dvl And Axin Complex); Inhibition Of The Dvl And Axin Complex Protein; CXXC-Type Since this Dvl-interacting protein is a novel protein, we designated it Idax (for inhibition of the Dvl and Axin complex). The mRNA of Idaxwas highly expressed in CXXC-type zinc finger protein 4. Gene -Experimental evidence at protein leveli.
Recombinant TET2 (1129-2002) protein is supplied at a concentration CXXC Finger Protein 4 (CXXC4) (C-Term) 抗体(PE) Primary Antibody Protein 4 , CXXC4, Inhibition of the Dvl and Axin Complex Protein, IDAX, MGC149872) ALTERNATE NAMES: CXXC4 Antibody: IDAX, IDAX, CXXC-type zinc finger protein 4, Inhibition of the Dvl and axin complex protein.
2013 May 2;497(7447):122-6. doi: 10.1038/nature12052. Epub 2013 Apr 7. PubMed Article Plasmids from Article. ID Plasmid Purpose ; 49446: FH-TET3-pEF: This plasmid … 01/05/2013 Dvl-Binding Protein IDAX (Inhibition Of The Dvl And Axin Complex) 1 2: Inhibition Of The Dvl And Axin Complex Protein 2 3: CXXC Finger 4 2: CXXC-Type Zinc Finger Protein 4 2: External Ids: HGNC: 24593 1 : Entrez Gene: 80319 2 : Ensembl: ENSG00000168772 7 : OMIM: 611645 5 : UniProtKB: Q9H2H0 3 : Export aliases for CXXC4 gene to outside databases.
DVL1-BINDING PROTEIN INHIBITOR OF DVL/AXIN COMPLEX; IDAX · TEXT · ▻ Cloning and Expression · ▻ Gene Function · ▻ Mapping · ▻ REFERENCES. CXXC4; CXXC finger protein 4; CXXC-type zinc finger protein 4; Dvl binding protein IDAX (inhibition of the Dvl and Axin complex); IDAX; CXXC finger 4; 21 Oct 2020 CXXC domain-containing protein IDAX (also known as CXXC4) can promote caspase activation probably via regulating gene transcription. CXXC DNA-binding domains (in the IDAX and TET3 genes) can bind The IDAX protein (367 aa) incorporates a 52-aa CXXC domain that is highly Dishevelled (Dvl/Dsh) protein is one of key components in Wnt signaling and plays For example, Dapper, Idax, and Naked cuticles inhibit canonical Wnt tial homology with Idax, a related protein previously shown to interact with the Wnt-signaling intermediate Dishevelled (Dvl). Indeed CXXC5 and Dvl co- localized IDAX downregulates TET2 protein by activating caspase pathway. 存放说明.
Utilize protein titer in real time to extract maximum value from every bioreactor run, with Tridex ™ from IDEX Health & Science. Engineered for convenience, Tridex allows you to achieve accurate titer measurements, which correlate to off-line HPLC, in only five minutes. As a TET2 binding partner, IDAX promotes degradation of TET2 protein (Ko et al., 2013). A family member of calcium-dependent proteases, calpain1, mediates TET2 degradation, which is likely to affect global 5hmC level and expression of certain lineage-specific genes in mESCs (Wang and Zhang, 2014 ). Since this Dvl-interacting protein is a novel protein, we designated it Idax (for inhibition of the Dvl and Axin complex).
Anti-Idax Antibody Products. Products (9) Write … IDAX: Description: CXXC finger protein 4 (HGNC Symbol) Chromosome: 4: Cytoband: q24: Chromosome location (bp) 104468312 - 104494901: Number of transcripts i. 1: Protein evidence: Evidence at transcript level : Protein class i. Ensembl: ENSG00000168772 (version 92.38) Entrez gene: 80319: UniProt: neXtProt: Antibodypedia : CXXC4 antibodies: PROTEIN BROWSER i.., CXXC4-201. PROTEIN … Plasmid Myc-Idax WT from Dr. Anjana Rao's lab contains the insert IDAX and is published in Nature.
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Protein expression was chemically induced by the addition of isopropyl-1-thio-β-d-galactoside (IPTG) to a final concentration of 1 mM and the cells were harvested 6 h later by centrifugation. Production of unlabeled rat Idax. The Idax construct used was the C-terminal half of the protein running from residue 109 to the C-terminus.
The cysteine-rich protein Idax acts as a negative regulator of Wnt signaling in mammals by interaction with Dvl in the region of the PDZ domain. In an effort to clarify the st … Dishevelled (Dvl) is the essential signal transduction component of both canonical and non-canonical Wnt signaling pathways.